000 02841cam a22004458a 4500
001 7083
003 BD-DhEWU
005 20190424020002.0
008 110512s2012 nyu b 001 0 eng
010 _a 2011020446
020 _a9780071603935 (hardcover : alk. paper)
020 _a007160393X (hardcover : alk. paper)
035 _a(DNLM)101560548
040 _aDNLM/DLC
_cDLC
_beng
_dBD-DhEWU
041 _aeng
050 0 0 _aRM301.4
_b.S52 2012
060 1 0 _aQV 38
082 0 0 _a615.7
_222
_bSHA 2012
100 1 _aShargel, Leon,
_d1941-
_98469
245 1 0 _aApplied biopharmaceutics & pharmacokinetics /
_cLeon Shargel, Andrew B.C. Yu, Susanna Wu-Pong.
246 1 _aApplied biopharmaceutics and pharmacokinetics
250 _a6th ed.
260 _aNew York :
_bMcGraw-Hill,
_cc2012.
263 _a1212
300 _axviii, 811 p. :
_c25 cm.
_b ill. ;
504 _aIncludes bibliographical references and index.
505 0 _aIntroduction to biopharmaceutics and pharmacokinetics -- Mathematic fundamentals in pharmacokinetics -- One-compartment open model: intravenous bolus administration -- Multicompartmental models : intravenous bolus administration -- Intravenous infusion -- Drug elimination and clearance -- Pharmacokinetics of oral absorption -- Multiple-dosage regimens -- Nonlinear pharmacokinetics -- Physiologic drug distribution and protein binding -- Drug elimination and hepatic clearance -- Pharmacogenetics -- Physiologic factors related to drug absorption -- Biopharmaceutic considerations in drug product design and in vitro drug product performance -- Drug product performance, in vivo : bioavailability and bioequivalence -- Impact of drug product quality and biopharmaceutics on clinical efficacy -- Modified-release drug products -- Targeted drug delivery systems and biotechnology products -- Relationship between pharmacokinetics and pharmacodynamics -- Application of pharmacokinetics to clinical situations -- Dosage adjustment in renal and hepatic disease.
_tTOC
520 _aA textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics. It provides you with a basic understanding of the principles of biopharmaceutics and pharmacokinetics and applies these principles to drug product development, drug product performance and drug therapy.
526 _aPharmacy
590 _aShaharima Parvin
650 0 _aBiopharmaceutics.
_99076
650 0 _aPharmacokinetics.
_99077
650 1 2 _aBiopharmaceutics.
_99078
650 2 2 _aModels, Chemical.
_91047
650 2 2 _aPharmacokinetics.
_99079
700 1 _aYu, Andrew B. C.,
_d1945-
_91049
700 1 _aWu-Pong, Susanna.
_91050
856 _3WorldCat details
_uhttp://www.worldcat.org/title/applied-biopharmaceutics-pharmacokinetics/oclc/726074708?referer=di&ht=edition
942 _2ddc
_cTEXT
_065
999 _c7083
_d7083