| 000 | 02739cam a22004214a 4500 | ||
|---|---|---|---|
| 001 | 5308 | ||
| 003 | BD-DhEWU | ||
| 005 | 20180115090546.0 | ||
| 008 | 040720s2005 nyua g b 001 0 eng d | ||
| 010 | _a 2004055962 | ||
| 020 | _a0071416137 | ||
| 020 | _a9780415334020 | ||
| 020 | _a0071416137 | ||
| 020 | _a0415334020 (alk. paper) | ||
| 035 | _a(OCoLC)56058036 | ||
| 040 |
_aDNLM/DLC _cDLC _dDLC _dBD-DhEWU _beng |
||
| 041 | _aeng | ||
| 050 | 0 | 0 |
_aRM263 _b.P56 2005 |
| 060 | 1 | 0 |
_aWB 330 _bP5357 2005 |
| 082 | 0 | 4 |
_a615.8 _bPHA 2005 |
| 245 | 0 | 0 |
_aPharmacotherapy : _ba pathophysiologic approach / _ceditors, Joseph T. Dipiro ... [et al.]. |
| 250 | _a6th ed. | ||
| 260 |
_aNew York : _bMcGraw-Hill, _cc2005. |
||
| 300 |
_axxxiii, 2802 p. : _bill. (some col.) ; _c27 cm. |
||
| 504 | _aIncludes bibliographical references and index. | ||
| 505 |
_tTOC _aCh. 1. Enzyme structure and function / Edward A. Meighen -- Ch. 2. Mechanisms / Bruce A. Palfey -- Cytochrome P450 example / W. Edward Lindup and Neil R. Kitteringham -- Carbonic anhydrase example / Claudiu T. Supuran, Andrea Scozzafava and Angela Casini -- Proteases example / Andre J. Niestroj and Hans-Ulrich Demuth -- Ch. 3. Kinetics / Irene Lee and Anthony J. Berdis -- Ch. 4. Enzyme inhibitors / Jure Stojan -- Ch. 5. Development of enzyme inhibitors as drugs / H. John Smith and Claire Simons -- Enzyme inhibitor examples for the treatment of breast cancer / L. W. Lawrence Woo -- Enzyme inhibitor examples for the treatment of prostate tumor / Samer Haidar and Rolf W. Hartmann -- Thrombin inhibitor examples / Torsten Steinmetzer -- HIV-1 protease drug development examples / Paul J. Ala and Chong-Hwan Chang -- Metalloproteinase-collagenase inhibitor examples / Claudiu T. Supuran and Andrea Scozzafava. |
||
| 520 | _aSummary: "Focusing on the development of enzyme inhibitors as therapeutic drugs, Enzymes and Their Inhibition: Drug Development provides a concise overview of the chemistry of major types of enzymes and their inhibitors. The opening chapters introduce the structure, substrates, kinetics, and mechanisms of enzymes. Subsequent chapters discuss the different types of enzyme inhibitors and the principles involved in developing them into effective drugs."--BOOK JACKET. | ||
| 526 | _aPharmacy | ||
| 590 | _aTahur Ahmed | ||
| 650 | 0 |
_aChemotherapy. _9135 |
|
| 650 | 0 |
_aPhysiology, Pathological. _98143 |
|
| 650 | 1 | 2 |
_aDrug Therapy. _99100 |
| 700 | 1 |
_aDiPiro, Joseph T. _99101 |
|
| 856 |
_3WorldCat details _uhttp://www.worldcat.org/title/pharmacotherapy-a-pathophysiologic-approach/oclc/56058036&referer=brief_results |
||
| 856 | 4 | 0 |
_3Ebook Fulltext _uhttp://lib.ewubd.edu/ebook/5308 |
| 942 |
_2ddc _cTEXT |
||
| 999 |
_c5308 _d5308 |
||
| 999 |
_c5308 _d5308 |
||