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008 920623s1993 bg a g b 001 0 eng d
010 _a 92022049
020 _a083850129X
020 _a9780838501290
035 _a(OCoLC)26163148
040 _aDNLM/DLC
_cDLC
_dDLC
_dBD-DhEWU
_beng
041 _aeng
050 0 0 _aRM301.4
_b.S52 1993
060 _aQV38 S531a
082 0 0 _a615.7
_bSHA 1993
100 1 _aShargel, Leon.
_d1941-
_98469
245 1 0 _aApplied biopharmaceutics and pharmacokinetics /
_cLeon Shargel, Andrew B.C. Yu.
250 _a3rd ed.
260 _aNorwalk, Conn. :
_bAppleton & Lange,
_cc1993.
300 _axxii, 625 p. :
_bill. ;
_c26 cm.
500 _aOnline version: Shargel, Leon, 1941- Applied biopharmaceutics and pharmacokinetics. Norwalk, Conn. : Appleton & Lange, c1993 (OCoLC)622296890
504 _aIncludes bibliographical references and index.
505 _tTOC
_aReview of mathematical fundamentals -- Rates and orders of reactions -- Introduction to pharmacokinetics -- One-compartment open model -- Multicompartment models -- Drug distribution and protein binding -- Physiologic factors related to drug absorption -- Biopharmaceutic consideration in drug product design -- Pharmacokinetics of drug absorption -- Bioavailability and bioequivalence -- Modified-release drug products and targeted drug delivery systems -- Drug clearance -- Hepatic elimination of drugs -- Intravenous infusion -- Multiple-dosage regimens -- Nonlinear pharmacokinetics -- Application of pharmacokinetics in clinical situations -- Dosage adjustment in renal disease -- Relationship between pharmacokinetics and pharmacologic response -- Physiologic pharmacokinetic models, statistical moment, and mean residence time.
526 _aPharmacy
590 _aTahur Ahmed
650 0 _aBiopharmaceutics.
_99123
650 0 _aPharmacokinetics.
_99124
650 2 _aBiopharmaceutics.
_99125
650 2 _aPharmacokinetics.
_99126
700 1 _aYu, Andrew B. C.
_91049
856 4 2 _3WorldCat details
_uhttp://www.worldcat.org/title/applied-biopharmaceutics-and-pharmacokinetics/oclc/26163148&referer=brief_results
942 _2ddc
_cTEXT
_014
999 _c4943
_d4943
999 _c4943
_d4943