TY - BOOK AU - Shargel,Leon AU - Yu,Andrew B.C. TI - Applied biopharmaceutics and pharmacokinetics SN - 083850129X AV - RM301.4 .S52 1993 U1 - 615.7 PY - 1993/// CY - Norwalk, Conn. PB - Appleton & Lange KW - Biopharmaceutics KW - Pharmacokinetics N1 - Online version: Shargel, Leon, 1941- Applied biopharmaceutics and pharmacokinetics. Norwalk, Conn. : Appleton & Lange, c1993 (OCoLC)622296890; Includes bibliographical references and index; TOC; Review of mathematical fundamentals -- Rates and orders of reactions -- Introduction to pharmacokinetics -- One-compartment open model -- Multicompartment models -- Drug distribution and protein binding -- Physiologic factors related to drug absorption -- Biopharmaceutic consideration in drug product design -- Pharmacokinetics of drug absorption -- Bioavailability and bioequivalence -- Modified-release drug products and targeted drug delivery systems -- Drug clearance -- Hepatic elimination of drugs -- Intravenous infusion -- Multiple-dosage regimens -- Nonlinear pharmacokinetics -- Application of pharmacokinetics in clinical situations -- Dosage adjustment in renal disease -- Relationship between pharmacokinetics and pharmacologic response -- Physiologic pharmacokinetic models, statistical moment, and mean residence time; Pharmacy UR - http://www.worldcat.org/title/applied-biopharmaceutics-and-pharmacokinetics/oclc/26163148&referer=brief_results ER -